@article{Fan2020-zb,
	abstract = {AIM: To evaluate the fractal feature of the retinal vasculature
               of normal eyes on a stereographic projected and montaged
               ultra-wide field (UWF) fluorescein angiography (FA). METHODS:
               Prospective, observational, cross-sectional study. Totally 59
               eyes of 31 normal subjects were imaged using the Optos 200Tx.
               Images obtained at different gaze angles stereographically
               projected and montaged. The early-phase UWF FA frames were
               processed to segment the retinal vasculature and the results
               were exported as binary masks. The fractal dimension (FD) was
               calculated using the box-counting method. RESULTS: The global FD
               for the entire retina was 1.6$\pm$0.04, with no difference
               between males and females (1.59$\pm$0.04 vs 1.61$\pm$0.04,
               P=0.084) or between right and left eyes (1.6$\pm$0.04 vs
               1.6$\pm$0.05, P=0.61). FD was non-uniformly distributed among
               four quadrants (P0.05). CONCLUSION: Fractal geometry is
               non-uniformly distributed across the retina in normal eyes and
               decreases from the fovea to the far-periphery. Subjects with an
               older age tend to have a smaller FD, however, the FD in the
               far-periphery does not appear to be influenced by age.},
	author = {Fan, W-Y and Fleming, A and Robertson, G and Uji, A and van Hemert, J and Singer, M and Sagong, M and Ip, M and Sadda, SR},
	date-added = {2024-01-05 15:33:05 +0000},
	date-modified = {2024-01-05 15:35:41 +0000},
	journal = {Int. J. Ophthalmol.},
	keywords = {retinal imaging},
	number = 7,
	pages = {1109--1114},
	title = {Fractal analysis of retinal vasculature in normal subjects on ultra-wide field fluorescein angiography},
	volume = 13,
	year = 2020}