@article{Jeong:2022tw,
	abstract = {Purpose: This study aims to evaluate choroidal vascular alterations in patients with central serous chorioretinopathy (CSC) using ultra-widefield (UWF) indocyanine green angiography (ICGA).

Methods: This was a retrospective case-control study conducted at a single tertiary eye center. In total, 36 eyes in patients with either unilateral (24 patients) or bilateral (six patients) treatment-na{\"\i}ve CSC and 30 eyes in 24 age-matched controls were evaluated. The number of quadrants with vortex vein engorgement on UWF ICGA was evaluated. Dilated choroidal vessels affecting the macula were regarded as extended vortex vein engorgement. Choroidal vascular hyperpermeability (CVH) area on late-phase ICGA was quantified using stereographic projection. The parameters were compared with clinical and optical coherence tomographic findings.

Results: Eyes with CSC had larger CVH area, thicker choroid, and more quadrants with vortex vein engorgement and extended vortex vein engorgement compared with control eyes (all P < 0.001). In patients with unilateral CSC, affected eyes had larger CVH area, thicker choroid, and more extended vortex vein engorgements compared with unaffected fellow eyes (all P < 0.001), but vortex vein engorgement did not significantly differ. CVH was significantly correlated with extended vortex vein engorgement (P < 0.001) and subfoveal choroidal thickness (P = 0.007).

Conclusions: The increased number and binocular symmetry of engorged vortex veins suggest an anatomical predisposition for CSC. CVH area and extended vortex vein engorgement were indicators of choroidal outflow congestion. These parameters may serve as diagnostic clues or predictors of disease development in eyes with CSC.

Keywords: Central serous chorioretinopathy; Choroidal vascular hyperpermeability; Indocyanine green angiography; Ultra-widefield; Vortex vein engorgement. },
	author = {S Jeong and W Kang and D Noh van Hemert, J and M Sagong},
	date-added = {2024-01-05 15:39:08 +0000},
	date-modified = {2024-01-05 15:39:08 +0000},
	journal = {Graefes Arch Clin Exp Ophthalmol},
	keywords = {retinal imaging},
	pages = {1887--1898},
	title = {Choroidal vascular alterations evaluated by ultra-widefield indocyanine green angiography in central serous chorioretinopathy},
	url = {https://doi.org/10.1007/s00417-021-05461-0},
	volume = {260},
	year = {2022},
	bdsk-url-1 = {https://doi.org/10.1007/s00417-021-05461-0}}